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90 Tablet/s $52.00 $0.58

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60 Tablet/s $37.80 $0.63

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30 Tablet/s $21.90 $0.73

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Generic Name : Mesalamine

Brand Name : Asacol

Manufacturer Name : Tillots Pharma

Product Code : CRX 196

Delivery Days : 10 to 15 working days

Strength : 400 Mg

Packaging : Tablet/s (Blister Packing)

Prescribed For : Ulcerative Colitis, Crohn's Disease


Asacol 400mg


Asacol 400mg, also known by its generic name mesalamine, is a medication that belongs to the class of drugs called aminosalicylates. It is primarily used in the treatment of inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn's disease. This prescription medication plays a crucial role in managing the symptoms of these chronic conditions, providing relief to patients suffering from the debilitating effects of gastrointestinal inflammation.

Ulcerative colitis is a form of inflammatory bowel disease characterized by inflammation of the colon and rectum. Crohn's disease, on the other hand, can affect any part of the gastrointestinal tract, leading to inflammation and damage. Both conditions involve an abnormal immune response, where the body's immune system mistakenly attacks the digestive tract.

Asacol 400mg is designed to target and treat the inflammation associated with these diseases. The active ingredient, mesalamine, is thought to exert its therapeutic effects locally in the gut. Mesalamine is an aminosalicylate, a compound derived from salicylic acid, which is known for its anti-inflammatory properties.

One of the distinctive features of Asacol is its delayed-release formulation. The 400mg tablet is coated with a special enteric coating, designed to release the medication in the terminal ileum and colon. This targeted release helps ensure that the active ingredient reaches the specific areas of inflammation, maximizing its effectiveness while minimizing systemic absorption.

The mechanism of action of mesalamine involves multiple pathways. It is believed to modulate the production of inflammatory mediators, such as prostaglandins and leukotrienes, which play a key role in the inflammatory response. Additionally, mesalamine may scavenge free radicals and inhibit the activity of certain enzymes involved in the inflammatory cascade.

Asacol is typically prescribed as a maintenance therapy to keep inflammatory bowel diseases in remission and prevent relapses. The dosage and duration of treatment may vary depending on the severity of the condition and the individual patient's response.

The efficacy of Asacol 400mg has been demonstrated in various clinical trials. Patients treated with mesalamine have shown improvements in symptoms such as abdominal pain, diarrhea, and rectal bleeding. Moreover, long-term use of Asacol has been associated with a reduction in the need for corticosteroids, which are potent but often accompanied by significant side effects.

Like any medication, Asacol is not without potential side effects. Common side effects include headache, nausea, abdominal pain, and flatulence. These side effects are generally mild and transient. However, in some cases, more serious adverse reactions such as allergic reactions, liver problems, or kidney issues may occur. Patients are advised to promptly report any unusual symptoms to their healthcare provider.

It is important for healthcare professionals to consider the patient's medical history and any potential contraindications before prescribing Asacol. Individuals with a history of hypersensitivity to salicylates or sulfasalazine, as well as those with kidney or liver impairment, may require careful monitoring or alternative treatment options.

Asacol 400mg is often part of a comprehensive treatment plan that may include dietary modifications, lifestyle changes, and other medications as needed. The goal of treatment is not only to alleviate symptoms during flare-ups but also to maintain long-term remission and improve the patient's quality of life.

In conclusion, Asacol 400mg is a valuable tool in the management of inflammatory bowel diseases. Its targeted release mechanism, coupled with the anti-inflammatory properties of mesalamine, makes it an effective option for patients dealing with the challenges of ulcerative colitis and Crohn's disease. While it is not a cure, Asacol provides much-needed relief and helps patients regain control over their lives by minimizing the impact of these chronic conditions. As with any medication, it is essential for healthcare providers and patients to work together to monitor its effects and make adjustments to the treatment plan as necessary.


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