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Generic Name : Eloxatin

Brand Name : Oxiplatin

Manufacturer Name : Fresenius Kabi

Product Code : CRX 73

Delivery Days : 10 to 15 working days

Strength : 100 Mg

Packaging : Injection (Vial/s Packing)


Oxitan 100mg/50ml



Oxitan 100mg/50ml is a pharmaceutical product that falls under the category of chemotherapy drugs. Chemotherapy is a widely used treatment for cancer, and Oxitan, also known as Oxaliplatin, is one of the key medications in this domain. This drug has played a significant role in the treatment of various types of cancer, especially colorectal cancer. In this comprehensive overview, we will explore Oxitan in detail, from its composition and mode of action to its indications, side effects, and administration.



Oxitan 100mg/50ml contains the active ingredient Oxaliplatin, which is a platinum-based compound. It is administered in the form of a clear, colorless to slightly yellow solution for infusion. This solution is available in vials of 50 ml, with each milliliter containing 2 mg of Oxaliplatin. The active ingredient, Oxaliplatin, is an essential component of many chemotherapy regimens due to its ability to inhibit the growth of cancer cells by interfering with their DNA.


Mechanism of Action:-

Oxaliplatin exerts its anticancer effects by a unique mechanism of action. It is classified as an alkylating agent, and it forms platinum-DNA adducts within cancer cells. These adducts lead to the cross-linking of DNA strands, resulting in DNA damage and the inhibition of DNA replication and transcription. This disruption of DNA function ultimately triggers the death of cancer cells.

Oxaliplatin is particularly effective against colorectal cancer. It is often used in combination with other chemotherapeutic agents, such as 5-fluorouracil (5-FU) and leucovorin, in a regimen known as FOLFOX (folinic acid, 5-FU, and Oxaliplatin), which has shown remarkable efficacy in treating advanced colorectal cancer.



Oxitan 100mg/50ml is primarily indicated for the treatment of colorectal cancer. It is used in various stages of colorectal cancer treatment, including adjuvant therapy following surgery, treatment of advanced and metastatic colorectal cancer, and as a neoadjuvant therapy to shrink tumors before surgical resection. This drug has significantly improved the prognosis and survival rates of patients with colorectal cancer, making it a cornerstone in the management of this disease.

In addition to colorectal cancer, Oxaliplatin is also being studied and used in the treatment of other types of cancer, such as pancreatic, gastric, and ovarian cancer. Its potential applications in these cancers continue to be a subject of ongoing research.



Oxitan 100mg/50ml is administered as an intravenous (IV) infusion. The specific dosage and infusion schedule may vary based on the patient's condition, the type and stage of cancer being treated, and the overall treatment plan. Typically, it is given in a clinical setting, such as a hospital or cancer treatment center, under the supervision of trained medical professionals.

The duration and frequency of Oxaliplatin infusions may also be adjusted to minimize the risk of side effects and to provide the most effective treatment for the patient. It is important for patients to follow their healthcare provider's instructions closely and attend all scheduled appointments.


Side Effects:-

Like many chemotherapy drugs, Oxitan 100mg/50ml can cause a range of side effects. These side effects can vary from person to person and may be influenced by the patient's overall health, the dose administered, and the specific cancer being treated. Common side effects associated with Oxaliplatin include:

    Neurotoxicity: Oxaliplatin is known to cause acute neurotoxicity, which often presents as cold-induced neuropathy, characterized by tingling, numbness, and pain in the hands and feet. This side effect is dose-dependent and tends to be reversible once treatment is completed.

    Nausea and Vomiting: Nausea and vomiting are common side effects of many chemotherapy drugs, including Oxaliplatin. Medications to prevent and manage these symptoms are often prescribed.

    Fatigue: Patients undergoing chemotherapy may experience fatigue, which can affect their daily activities. It is essential to get adequate rest during treatment.

    Gastrointestinal Disturbances: Oxaliplatin can lead to diarrhea, constipation, and abdominal pain. Management may involve dietary changes and medication.

    Hematological Effects: Chemotherapy can affect blood cell counts, leading to an increased risk of infections, anemia, and bleeding. Regular blood tests are used to monitor these parameters.



Precautions and Warnings:-

Before starting treatment with Oxitan 100mg/50ml, patients should inform their healthcare provider about their medical history, existing medical conditions, and any medications they are currently taking. Some precautions and warnings associated with Oxaliplatin treatment include:

    Pregnancy and Breastfeeding: Oxaliplatin can harm an unborn baby, so it is not recommended for use during pregnancy. It is also not recommended during breastfeeding, as it may pass into breast milk.

    Kidney Function: Patients with impaired kidney function may require dosage adjustments, as Oxaliplatin is primarily excreted by the kidneys.

    Hypersensitivity: Patients with known hypersensitivity to platinum-containing compounds should not receive Oxaliplatin.

    Neurological Disorders: Individuals with a history of neurological disorders may be at a higher risk of experiencing neurotoxicity with Oxaliplatin. The healthcare team will carefully consider the potential benefits and risks of treatment in these cases.



Oxitan 100mg/50ml, or Oxaliplatin, is a vital component in the treatment of colorectal cancer and holds promise in the management of other cancers as well. Its unique mechanism of action, when combined with other chemotherapeutic agents, has significantly improved the outcomes for many cancer patients. However, it is not without its side effects, which need to be closely monitored and managed by healthcare professionals. Patients considering or undergoing Oxaliplatin treatment should engage in open and regular communication with their medical team to ensure the best possible care and outcomes. The development and use of drugs like Oxitan continue to contribute to the advancement of cancer treatment and the improvement of patient quality of life in the face of this challenging disease.


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