| Pack Size/Qty | Price | Unit Price | |
| 10 Tube/s | $35.00 | $3.50 | |
| 6 Tube/s | $22.20 | $3.70 | |
| 3 Tube/s | $12.24 | $4.08 | |
| 1 Tube | $4.50 | $4.50 |
Generic Name : Piroxicam
Brand Name : Feldene
Manufacturer Name : Cipla Ltd - Pharmaceutical Company
Product Code : CRX 108
Delivery Days : 10 to 15 working days
Strength : 30 gm
Packaging : Tube Cream
Piroxicam gel is a topical non-steroidal anti-inflammatory drug (NSAID) that is widely used to alleviate pain and inflammation associated with various musculoskeletal conditions. It belongs to the oxicam class of NSAIDs and is a well-established medication in the realm of pain management. This article will provide a detailed description of piroxicam gel, its uses, benefits, side effects, precautions, and more, encompassing a wide array of information to help you understand this medication better.
Piroxicam gel primarily consists of the active pharmaceutical ingredient (API) piroxicam, which is a non-selective NSAID. The gel formulation typically includes piroxicam at a concentration of 0.5% to 1%. This percentage may vary depending on the brand and formulation. Besides the active ingredient, piroxicam gel may contain various excipients such as gelling agents, preservatives, and penetration enhancers to facilitate drug delivery through the skin.
Piroxicam belongs to the NSAID class, which works by inhibiting enzymes called cyclooxygenases (COX-1 and COX-2). These enzymes are responsible for the production of prostaglandins, which are chemical messengers that promote inflammation, pain, and fever. By inhibiting COX enzymes, piroxicam reduces the production of prostaglandins, subsequently diminishing pain and inflammation at the site of application.
Piroxicam gel is indicated for the management of various musculoskeletal conditions, including but not limited to:
Osteoarthritis: Piroxicam gel can be applied topically to relieve pain and inflammation associated with osteoarthritis, a degenerative joint disease common in the elderly.
Rheumatoid Arthritis: It is also effective in reducing pain and inflammation in rheumatoid arthritis, an autoimmune condition affecting the joints.
Soft Tissue Injuries: Piroxicam gel is used for the treatment of acute injuries such as sprains, strains, and contusions.
Tendinitis: In conditions like tendinitis, piroxicam gel can provide local relief from pain and swelling.
Other Inflammatory Conditions: Piroxicam gel may be prescribed for various other inflammatory conditions of the musculoskeletal system.
Piroxicam gel offers several advantages as a topical NSAID:
Localized Action: When applied topically, piroxicam gel exerts its effects primarily at the site of application, providing localized pain relief without affecting the entire body.
Lower Systemic Absorption: Compared to oral NSAIDs, topical piroxicam has lower systemic absorption, reducing the risk of systemic side effects such as gastrointestinal irritation.
Ease of Use: It is easy to apply piroxicam gel directly to the affected area, and it is well-tolerated by most patients.
Quick Onset: The gel formulation allows for rapid absorption and onset of action, providing relatively fast relief.
Reduced Drug Interactions: Topical application of piroxicam results in lower drug interactions when compared to oral NSAIDs.
Piroxicam gel should be used as directed by a healthcare professional. Generally, it is applied to the affected area three to four times a day, with a thin layer of the gel gently massaged into the skin. It is crucial to wash hands after application and avoid contact with eyes, mucous membranes, or broken skin. The duration of use and the frequency may vary based on the specific condition and the product's instructions.
While piroxicam gel is generally considered safe when used as prescribed, there are certain precautions and contraindications to be aware of:
Allergies: Individuals with known hypersensitivity to piroxicam or any of its components should avoid its use.
Open Wounds: The gel should not be applied to open wounds, damaged skin, or mucous membranes.
Pregnancy and Breastfeeding: Pregnant and breastfeeding women should consult with their healthcare provider before using piroxicam gel, as there may be potential risks to the fetus or infant.
Children: The safety and effectiveness of piroxicam gel in children have not been well-established, so it is generally not recommended for use in pediatric patients.
Underlying Medical Conditions: Patients with a history of stomach ulcers, bleeding disorders, or kidney problems should exercise caution and discuss the use of piroxicam gel with their healthcare provider.
Other Medications: Patients taking other medications, especially oral NSAIDs, blood thinners, or corticosteroids, should inform their healthcare provider to prevent potential drug interactions.
Avoid Sun Exposure: It's advisable to avoid direct exposure to sunlight or artificial UV light on the treated area to prevent photosensitivity reactions.
Piroxicam gel is generally well-tolerated, but like all medications, it can have side effects. Common side effects may include skin irritation, itching, redness, and a warm or burning sensation at the application site. These side effects are usually mild and transient. However, if any severe skin reactions or allergic symptoms (such as rash, swelling, or difficulty breathing) occur, it is essential to discontinue use and seek immediate medical attention.
Piroxicam gel may interact with other medications, so it is crucial to inform your healthcare provider about all the drugs you are taking. Some potential interactions include:
Oral NSAIDs: Concurrent use of oral NSAIDs and piroxicam gel may increase the risk of systemic side effects.
Anticoagulants: Piroxicam may enhance the effects of anticoagulant medications, potentially increasing the risk of bleeding.
Corticosteroids: The use of piroxicam gel with corticosteroids may elevate the risk of gastrointestinal irritation.
Other Topical Medications: Using multiple topical medications on the same area may increase the risk of skin irritation.
Overdosing on piroxicam gel is uncommon due to its limited systemic absorption. However, if a substantial amount is ingested or excessive gel is applied, it is essential to seek medical attention promptly. Symptoms of overdose may include nausea, vomiting, stomach pain, drowsiness, and, rarely, more severe gastrointestinal or central nervous system effects.
Piroxicam gel should be stored at room temperature, away from direct sunlight and moisture, and out of reach of children.
Piroxicam gel is a valuable topical medication for managing pain and inflammation associated with various musculoskeletal conditions. Its localized action, reduced systemic absorption, and ease of use make it a practical choice for patients seeking relief from these ailments. However, like any medication, it should be used under the guidance of a healthcare professional, adhering to prescribed dosages and instructions. It's important to be aware of potential side effects, contraindications, and drug interactions to ensure safe and effective use. If you're considering piroxicam gel for your condition, consult with your healthcare provider to determine whether it's the right choice for
