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Generic Name : estradiol

Brand Name : estrace

Manufacturer Name : Bayer

Product Code : CRX 141

Delivery Days : 10 to 15 working days

Strength : 2 Mg

Packaging : Tablet/s (Blister Packing)


Progynova 2mg


Progynova 2mg is a medication that contains estradiol valerate, a synthetic form of the female sex hormone estrogen. It is commonly prescribed to treat various medical conditions in women, primarily related to hormonal imbalances and menopausal symptoms. In this comprehensive description, we will delve into the various aspects of Progynova 2mg, including its composition, indications, dosage, side effects, and precautions.



Progynova 2mg is primarily composed of estradiol valerate, which is a synthetic estrogen hormone. This hormone is similar to the naturally occurring estrogen in a woman's body. Each Progynova 2mg tablet contains 2 milligrams of estradiol valerate. It is available in oral tablet form, making it convenient for patients to take as part of their treatment regimen.



Progynova 2mg is prescribed for several medical conditions and situations, including:

    Menopausal Symptoms: One of the most common uses of Progynova 2mg is to relieve the symptoms associated with menopause. These symptoms can include hot flashes, night sweats, mood swings, and vaginal dryness. Estradiol valerate helps alleviate these symptoms by replacing the declining estrogen levels in menopausal women.

    Hormone Replacement Therapy (HRT): Progynova 2mg is often used as a component of hormone replacement therapy for postmenopausal women. It helps maintain hormonal balance and can reduce the risk of osteoporosis and cardiovascular diseases in this population.

    Hypogonadism: In cases of primary ovarian failure or hypogonadism, where the ovaries do not produce enough estrogen, Progynova 2mg can be prescribed to supplement estrogen levels.

    Gender Affirmation Therapy: For transgender women undergoing gender transition, estradiol valerate can be a component of hormone therapy to develop female secondary sexual characteristics, such as breast development and softening of the skin.

    Endometrial Hyperplasia Prevention: Progynova 2mg is sometimes used to prevent endometrial hyperplasia in women who have an intact uterus and are prescribed progestin as well, which helps protect the endometrial lining from excessive estrogen stimulation.



The dosage of Progynova 2mg can vary depending on the specific medical condition being treated and individual patient needs. It is essential to follow the prescribed dosage and instructions provided by a healthcare professional. In general, for the treatment of menopausal symptoms and hormone replacement therapy, a common starting dose is 1 to 2 mg of Progynova daily. The dose may be adjusted as needed, but it is recommended to use the lowest effective dose for the shortest duration to minimize potential risks.

For transgender hormone therapy, the dosage may be different, and it is crucial to follow the guidance of a qualified healthcare provider experienced in gender-affirming care


Side Effects:-

Like any medication, Progynova 2mg can have potential side effects. It is important to be aware of these and discuss them with your healthcare provider. Common side effects may include:

    Breast Tenderness: Some women may experience breast tenderness or swelling when taking Progynova.

    Nausea: Nausea can occur in some individuals, but taking the medication with food can help alleviate this side effect.

    Headache: Headaches are a possible side effect, but they are usually mild and transient.

    Vaginal Bleeding: Irregular vaginal bleeding or spotting can occur, especially during the first few months of treatment. This is more common if Progynova is not taken in combination with a progestin.

    Mood Changes: Some women may experience mood swings or changes in mood. If these changes are severe or persistent, it is important to consult a healthcare provider.

    Leg Cramps: Leg cramps have been reported in some cases.

    Fluid Retention: Retaining water or edema may occur in some individuals.

It is important to note that not everyone will experience these side effects, and many individuals tolerate Progynova well. Additionally, serious side effects such as blood clots, stroke, and breast cancer are rare but possible. Discuss any concerns or unusual symptoms with your healthcare provider promptly.



Before starting Progynova 2mg or any hormone replacement therapy, it is crucial to discuss your medical history and any pre-existing conditions with your healthcare provider. Certain individuals may not be suitable candidates for this medication. Here are some key precautions:

    Breast Cancer History: If you have a history of breast cancer, it is essential to discuss the potential risks and benefits of hormone replacement therapy with your healthcare provider.

    Blood Clot Risk: Progynova 2mg can increase the risk of blood clots, especially in women with a history of blood clots or other risk factors like smoking or obesity.

    Liver Disease: Individuals with severe liver disease or impaired liver function should use Progynova with caution, as the liver metabolizes the medication.

    Cardiovascular Disease: Those with a history of heart disease or stroke should carefully consider the risks and benefits of hormone replacement therapy.

    Smoking: Smoking while using Progynova can increase the risk of cardiovascular complications. It is advisable to quit smoking if you are taking this medication.

    Regular Check-ups: Regular follow-up appointments with your healthcare provider are essential to monitor your response to the medication and address any concerns or side effects.

    Interaction with Other Medications: Inform your healthcare provider about all the medications you are taking, as certain drugs can interact with Progynova.



Progynova 2mg is a medication containing estradiol valerate, primarily used in the treatment of menopausal symptoms, hormone replacement therapy, and other hormone-related conditions. While it can be highly effective in alleviating symptoms and improving the quality of life for many women, it is essential to use it under the guidance of a healthcare provider who can assess your individual needs and monitor for any potential side effects or complications. Always follow your healthcare provider's recommendations and attend regular check-ups to ensure safe and effective treatment.


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